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Item number: TGM-T5482-100mg

Description: TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels. Target: Prostaglandin Receptor. Smiles: COc1cc(\C=C\C(=O)NCCn2c(C)cc3ccccc23)cc(OC)c1OC. References: Jiang J , Ganesh T , Du Y , et al. Small...

Application:	Brain penetrant EP2 antagonist
CAS	1164462-05-8
MW:	394.46 D

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TG4-155

Item number: Cay17639-10

Prostaglandin E2 (PGE2) evokes distinct responses through four different 'E prostanoid' (EP) receptors. EP2 is a G protein-coupled receptor that has diverse roles, including those in cancer, inflammation, and neuroprotection. TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less...

Keywords:	(2E)-N-[2-(2-methyl-1H-indol-1-yl)ethyl]-3-(3,4,5-trimethoxyphenyl)-2-propenamide
Application:	Brain penetrant EP2 antagonist
CAS	1164462-05-8
MW:	394.5 D

From 84.00€ *

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