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Nitecapone
Item number: TGM-T7831-100mg
Description: Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver). Target: Transferase, Others. Smiles: CC(=O)C(=Cc1cc(O)c(O)c(c1)[N+]([O-])=O)C(C)=O. References: P.T. Männistö, Kaakkola S . Catechol-O-methyltransferase (COMT): Biochemistry, molecular biology, pharmacology, and...
| Application: | Targets catechol O-methyltransferase [EC:2.1.1.6] (COMT) |
| CAS | 116313-94-1 |
| MW: | 265.22 D |
From 42.00€
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Nitecapone
Item number: Cay18656-10
Nitecapone is a reversible inhibitor of S-catechol-O-methyltransferase (S-COMT, IC50 = 300 nM in rat liver). It is selective for S-COMT over tyrosine hydroxylase, dopamine-beta-hydroxylase, DOPA decarboxylase, monoamine oxidase A (MAO-A), and MAO-B (IC50s = >1 µM for all). In vivo, nitecapone inhibits liver,...
| Keywords: | OR-462, 3-[(3,4-dihydroxy-5-nitrophenyl)methylene]-2,4-pentanedione |
| Application: | S-COMT inhibitor |
| CAS | 116313-94-1 |
| MW: | 265.2 D |
From 100.00€
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