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Item number: Cay16295-1

Metabotropic glutamate receptors (mGluRs) modulate brain excitability through diverse mechanisms. VU0361737 is a selective positive allosteric modulator (PAM) of mGluR4, displaying EC50 values of 110 and 240 nM for rat and human receptors, respectively. It has weak or no activity at other mGluRs. VU0361737 passes...

Keywords:	N-(4-chloro-3-methoxyphenyl)-2-pyridinecarboxamide
Application:	mGluR4 positive allosteric modulator
CAS	1161205-04-4
MW:	262.7 D

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