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Item number: Cay10683-1

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels in the central and peripheral nervous system. SR 16584 is an antagonist of the alpha3beta4 nAChR subtype (IC50 = 10.2 µM). It shows selective binding of the alpha3beta4 subtype compared to the alpha4beta2 and alpha7 subtypes (Ki values of...

Keywords:	3-dihydro-1-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-2H-indol-2-one
Application:	alpha3beta4 nAChR antagonist
CAS	1150153-86-8
MW:	270.4 D

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SR 16584

Item number: TGM-T23388-10mg

Description: alpha3beta4 nAChR antagonist. Target: Others. Smiles: O=C1N(C=2C(C1)=CC=CC2)[C@@H]3C[C@@]4(N(C)[C@](C3)(CCC4)[H])[H]. References: Solt L A, Kumar N, He Y, et al. Identification of a selective RORgamma ligand that suppresses Th17 cells and stimulates T regulatory cells[J]. ACS chemical biology, 2012,...

CAS	1150153-86-8
MW:	270.37 D

From 83.00€ *

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