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Item number: Cay34662-1

Trabectedin is an alkaloid that has been found in E. turbinata and has anticancer activity. It is a guanine-specific DNA alkylating agent and an antagonist of the pregnane X receptor (PXR, IC50 = ~3 nM in a reporter assay). Trabectedin reduces viability of DU145 and PC3 human prostate cancer stem cells in a...

Keywords:	Ecteinascidin 743, ET-743, NSC 648766,...
Application:	Alkaloid, Anticancer agent, PXT antagonist, Guanine-specific DNA alkylating agent
CAS	114899-77-3
MW:	761.8 D

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