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Item number: TGM-T8537-25mg

Description: Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 µM and 7 µM, respectively). Target: Aurora Kinase. Smiles: C(=C/1\C=2C(NC1=O)=CC=CC2)\C3=C(O)C=CC(O)=C3. References: Iliana A Kesisova, et al. Tripolin A, a Novel Small-Molecule...

Application:	Aurora A kinase inhibitor
CAS	1148118-92-6
MW:	253.25 D

800.00€ *

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Tripolin A

Item number: AG-CR1-3520-M001

Soluble in DMSO (at least 10 mg/ml). Specific non-ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase.

Keywords:	(3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one
Application:	Aurora A kinase inhibitor
CAS	1148118-92-6
MW:	253,3 D

From 88.00€ *

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