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Fascaplysin chloride
Item number: TGM-T27305-1mg
Description: Fascaplysin is a cyclin D kinase 4/ cyclin D1 inhibitor (IC50 = 0.35 µM). Fascaplysin induces caspase mediated crosstalk between autophagy and apoptosis through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells. Target: Others. Smiles:...
| Keywords: | NSC 622398, NSC622398, Fascaplysin, NSC-622398 |
| Application: | CDK4/cyclin D1 inhibitor |
| CAS | 114719-57-2 |
| MW: | 306.75 D |
From 120.00€
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Fascaplysin (chloride)
Item number: Cay21715-1
Fascaplysin is an inhibitor of cyclin D kinase 4/ cyclin D1 (IC50 = 0.35 µM) that was originally isolated from the marine sponge Thorectandra. It is significantly less selective for Cdk6/cyclin D1 (IC50 = 3.4 µM) and does not inhibit other Cdks and tyrosine kinases. Fascaplysin is reported to have antiproliferative...
| Keywords: | NSC 622398, 12,13-dihydro-13-oxo-pyrido[1,2-a:3,4-b']diindol-5-ium, monochloride |
| Application: | CDK4/cyclin D1 inhibitor |
| CAS | 114719-57-2 |
| MW: | 306.7 D |
From 66.00€
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