3 products were found matching "1146699-66-2"!
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Avagacestat
Item number: TGM-T6249-100mg
Description: Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable gamma-secretase inhibitor of Abeta40 and Abeta42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2. Target: Gamma-secretase. Smiles:...
| Keywords: | BMS-708163 |
| Application: | Dementia therapeutic agent, gamma-Secretase inhibitor |
| CAS | 1146699-66-2 |
| MW: | 520.89 D |
From 57.00€
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Avagacestat
Item number: Cay16711-1
gamma-Secretase is a protease complex that cleaves single-pass transmembrane proteins, such as Notch receptors and beta-amyloid precursor protein (APP), within the transmembrane domain. Avagacestat is a potent, orally bioavailable inhibitor of gamma-secretase that more potently inhibits the cleavage of APP to...
| Keywords: | BMS 708163,... |
| Application: | gamma-secretase inhibitor |
| CAS | 1146699-66-2 |
| MW: | 520.9 D |
From 61.00€
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BMS-708163
Item number: LKT-B5075.1
gamma-Secretase inhibitor.
| Keywords: | Avagacestat, BMS708163 |
| Application: | gamma-secretase inhibitor |
| CAS | 1146699-66-2 |
| MW: | 520.88 D |
From 94.00€
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