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2',2'-Difluorodeoxyuridine
Item number: TGM-T67291-100mg
Description: 2',2'-Difluorodeoxyuridine (dFdU), the major metabolite of Gemcitabine, exhibits anticancer and antitumor activities, shows radiosensitization under hypoxic conditions, and can be used to study pancreatic cancer. Target: Drug Metabolite. Smiles: OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C(F)(F)[C@@H]1O....
| Keywords: | dFdU, 2',2'-Difluoro-2'-deoxyuridine |
| Application: | Gemcitabine active metabolite |
| CAS | 114248-23-6 |
| MW: | 264.18 D |
From 34.00€
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2',2'-Difluoro-2'-deoxyuridine
Item number: Cay11689-5
2',2'-Difluoro-2'-deoxyuridine is an active metabolite of the anticancer nucleoside analog gemcitabine (Cay-11690). It is formed by deamination of gemcitabine by cytidine deaminase in the liver. 2',2'-Difluoro-2'-deoxyuridine is cytotoxic to HepG2 and A549 cancer cells (IC50s = 3.13 and 3.92 µM, respectively). It...
| Keywords: | dFdU, 2'-deoxy-2',2'-difluoro-uridine |
| Application: | Gemcitabine active metabolite |
| CAS | 114248-23-6 |
| MW: | 264.2 D |
From 67.00€
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