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PNU-74654
PNU-74654

Item number: TGM-T7204-100mg

Description: PNU 74654 binds to beta-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway. Target: Apoptosis, Wnt/beta-catenin. Smiles: Cc1ccc(\C=N\NC(=O)c2ccccc2Oc2ccccc2)o1. References: Leal, Letícia F, Bueno A...
Application: Tcf4/beta-catenin interaction inhibitor
CAS 113906-27-7
MW: 320.34 D
From 52.00€ *
Review
PNU 74654
PNU 74654

Item number: Cay16349-1

The Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers. PNU 74654 binds to beta-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway. Treatment of human...
Keywords: 2-phenoxy-benzoic acid, 2-[(5-methyl-2-furanyl)methylene]hydrazide
Application: Tcf4/beta-catenin interaction inhibitor
CAS 113906-27-7
MW: 320.3 D
From 49.00€ *
Review