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TAK-960
Item number: TGM-T7200-100mg
Description: TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively. Target: PLK. Smiles: COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc2N(C)C(=O)C(F)(F)CN(C3CCCC3)c2n1. References: Klauck P J , Bagby S M , Capasso A , et al. Antitumor...
| Application: | PLK1 inhibitor |
| CAS | 1137868-52-0 |
| MW: | 561.6 D |
From 58.00€
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TAK-960
Item number: Cay17701-1
Polo-like kinases (Plks) are serine/threonine kinases with key roles in cell cycling. TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively. It exhibits greater than 20-fold selectivity for Plk1 over FAK, MLCK, and the...
| Keywords: | 4-[(9-cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-me... |
| Application: | PLK1 inhibitor |
| CAS | 1137868-52-0 |
| MW: | 561.6 D |
From 85.00€
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