- Search results for 1135242-13-5
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2 products were found matching "1135242-13-5"!
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Item number: TGM-T3619-100mg
Description: VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM, Pec50: 6.37 ± 0.15). Target: AChR. Smiles: Cl.CCOC(=O)N1CCC(CC1)NCCNC(=O)c1ccccc1C. References: Digby GJ, et al. ACS Chem Neurosci. 2012 Dec...
Keywords: | ML071 hydrochloride, VU 0357017 hydrochloride, CID-25010775 |
Application: | M1 muscarinic acetylcholine allosteric agonist |
CAS | 1135242-13-5 |
MW: | 369.89 D |
From 35.00€
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Item number: Cay11939-1
VU0357017 is an allosteric agonist of M1 muscarinic acetylcholine receptors (mAChRs, Ki = 9.91 µM in CHO cells). In vitro, it is selective for M1 over M2-M5 mAChRs (Kis = 21.4-50 µM in CHO cells). VU0357017 induces concentration-dependent increases in calcium mobilization and activates the ERK signaling pathway with...
Keywords: | CID-25010775, 4-[[2-[(2-methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid, ethyl ester, monohydrochloride |
Application: | M1 muscarinic acetylcholine allosteric agonist |
CAS | 1135242-13-5 |
MW: | 369.9 D |
From 34.00€
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