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Item number: Cay18257-1

Imatinib-d3 is intended for use as an internal standard for the quantification of imatinib (Cay-13139) by GC- or LC-MS. Imatinib is an inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit. It inhibits ligand-stimulated autophosphorylation of PDGFR and c-Kit (IC50s = ~0.3 and ~0.1 µM,...

Keywords:	Genfatinib-d3, 4-[[4-(methyl-d3)-1-piperazinyl]methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide
Application:	Bcr-Abl / PDGFRA / PDGFRB / c-KIT inhibitor, internal control
CAS	1134803-18-1
MW:	496.6 D

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