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U-73122
Item number: TGM-T6243-100mg
Description: U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN. Target: Lipoxygenase, Ferroptosis, Phospholipase. Smiles: COc1ccc2[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CCc2c1)NCCCCCCN1C(=O)C=CC1=O. References: Bleasdale JE, et al. J Pharmacol Exp Ther, 1990,...
| Keywords: | U73122 |
| Application: | PLC inhibitor |
| CAS | 112648-68-7 |
| MW: | 464.64 D |
From 33.00€
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U-73122
Item number: Cay70740-5
U-73122 is an inhibitor of PLC-dependent processes, however, the mechanism of action remains unclear. The IC50 values for inhibition of platelet aggregation induced by collagen or thrombin are 0.6 and 5 µM, respectively. It also exhibits inhibitory activity against HIV-1 integrase with an IC50 value of 7 µM.Formal...
| Keywords: | 1-[6-[[(17beta)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione |
| Application: | Lipid signaling studies |
| CAS | 112648-68-7 |
| MW: | 464.6 D |
From 28.00€
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U-73122
Item number: AG-CR1-3698-M005
White to off-white solid. Soluble in methylene chloride or chloroform (10mg/ml). Slightly soluble in DMSO (2mg/ml), DMF (2mg/ml) or 100% ethanol (1mg/ml). Sparingly soluble in aqueous solutions. See also Solubility Note below. Chemical. CAS: 112648-68-7. Formula: C29H40N2O3. MW: 464.6. Gasdermin D N-terminal...
| Keywords: | 1-[6-[[(17beta)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione |
| CAS | 112648-68-7 |
| MW: | 464,6 D |
From 22.00€
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