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Item number: Cay40427-10

Lifitegrast is an inhibitor of the protein-protein interaction between lymphocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1). It binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s = 2.98 and 9 nM, respectively) and inhibits the...

Keywords:	SAR 1118-023,...
Application:	LFA-1/ICAM-1 interaction inhibitor
CAS	1119276-80-0
MW:	637.5 D

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