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Bexagliflozin
Item number: TGM-T7217-100mg
Description: Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2 and 5.6 µM for human SGLT1. Target: SGLT. Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCCOC3CC3)cc2)c1. References: Zhang W , Welihinda A ,...
| Keywords: | EGT0001442, THR-1442, EGT1442 |
| Application: | Targets solute carrier family 5 (sodium/glucose cotransporter), member 2 (SLC5A2, SGLT2) |
| CAS | 1118567-05-7 |
| MW: | 464.94 D |
From 65.00€
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EGT-1442
Item number: Cay21359-1
EGT-1442 is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 5.6 µM and 2 nM for human SGLT1 and SGLT2, respectively. It produces a stable urinary excretion of glucose in rats and dogs with ED50 values of 0.38 and 0.09 mg/kg, respectively, and reduces HbA(1c) and blood...
| Keywords: | THR-1442, (1S)-1,5-anhydro-1-C-[4-chloro-3-[[4-[2-(cyclopropyloxy)ethoxy]phenyl]methyl]phenyl]-D-glucitol |
| Application: | SGLT2 inhibitor |
| CAS | 1118567-05-7 |
| MW: | 464.9 D |
From 44.00€
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