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Item number: TGM-T8972-100mg

Description: FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 µM,CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 µM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses....

Application:	Cdk9 inhibitor
CAS	1113044-49-7
MW:	315.41 D

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FIT-039

Item number: Cay36555-1

FIT-039 is an inhibitor of cyclin-dependent kinase 9 (Cdk9, IC50 = 5.8 µM for Cdk9/cyclin T1). It is selective for Cdk9/cyclin T1 over Cdk4/cyclin D3 at 30 µM and Cdk2/cyclin A2, Cdk2/cyclin E1, Cdk5/p25, Cdk6/cyclin D3, and Cdk7/cyclin/MAT1 at 10 µM but also inhibits GSK3alpha, GSK3beta, PKN1, haspin, p70S6K,...

Keywords:	N-[5-fluoro-2-(1-piperidinyl)phenyl]-4-pyridinecarbothioamide
Application:	Cdk9 inhibitor
CAS	1113044-49-7
MW:	315.4 D

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