2 products were found matching "1112978-84-3"!

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Item number: AG-MR-C0023-M001

Soluble in DMSO or ethanol. Stock solutions can be made up to 10 mM in DMSO. Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3 alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against...

Keywords:	(5Z)-5-(1,3-Benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4one
Application:	DYRK / CLK inhibitor
CAS	1112978-84-3
MW:	307,3 D

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Leucettine L41

Item number: Cay29225-1

Leucettine L41 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), DYRK2, CDC-like kinase 1 (CLK1), and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 µM, respectively). It also inhibits GSK3alpha/beta and Pim1 with IC50 values of 0.41 and 4.1 µM, respectively. It inhibits...

Keywords:	(5Z)-5-(1,3-benzodioxol-5-ylmethylene)-3,5-dihydro-2-(phenylamino)-4H-imidazol-4-one
Application:	DYRK1A / DYRK2 / CLK1 / CLK3 inhibitor
CAS	1112978-84-3
MW:	307.3 D

From 84.00€ *

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