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Takinib
Takinib

Item number: Cay24161-5

Takinib is a TGF-beta-activated kinase 1 (TAK1) inhibitor (IC50 = 9.5 nM). It is selective for TAK1 over IRAK1, IRAK4, GCK, Clk2, and MINK1 (IC50s = 390, 120, 430, 430, and 1,900 nM, respectively). Takinib increases caspase-3/-7 activity and inhibits proliferation of TNF-alpha-stimulated, but not unstimulated,...
Keywords: N1-(1-propyl-1H-benzimidazol-2-yl)-1,3-benzenedicarboxamide
Application: TAK1 (MAP3K7) inhibitor
CAS 1111556-37-6
MW: 322.4 D
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