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Item number: TGM-T9357-100mg

Description: Ro 5212773 (Epptb) is a selective TAAR1 antagonist. Target: Others. Smiles: CCOc1cccc(NC(=O)c2ccc(N3CCCC3)c(c2)C(F)(F)F)c1. References: Bradaia A , Trube G , Stalder H , et al. The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic...

Keywords:	Epptb
Application:	TAAR1 antagonist
CAS	1110781-88-8
MW:	378.39 D

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EPPTB

Item number: Cay34330-10

EPPTB is an antagonist of trace amine-associated receptor 1 (TAAR1, Ki = 0.9 nM for the mouse receptor). It selectively inhibits beta-phenylethylamine-induced cAMP production in HEK293 cells expressing mouse TAAR1 over human or rat TAAR1 (IC50s = 27.5, 7,487, and 4,539 nM, respectively). EPPTB (10 nM) reduces...

Keywords:	Ro 5212773, N-(3-ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)-benzamide
Application:	TAAR1 antagonist
CAS	1110781-88-8
MW:	378.4 D

From 66.00€ *

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