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Item number: TGM-T14293-1mg

Description: Annonacin is an acetogenin that promotes cytotoxicity by inhibiting the mitochondrial complex and acts as the active agent in Graviola leaf extract, inhibiting sodium/potassium (NKA) and sarcoplasmic reticulum (SERCA) ATPase pumps[1]. Target: Others. Smiles: CCCCCCCCCC...

CAS	111035-65-5
MW:	596.88 D

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Annonacin

Item number: Cay22415-500

Annonacin is a potent and lipophilic acetogenin from A. muricata that inhibits mitochondrial complex I (IC50 = 54.8 nM)., Annonacin induces ATP depletion, tau pathologies, and dopaminergic cell death in rats (EC50s = 134, 44.1, and 60.8 nM, respectively). Quantities of annonacin in the fruit and teas made from...

Keywords:	5S-5-methyl-3-[(2R,8R,13R)-2,8,13-trihydroxy-13-[(2R,5R)-tetrahydro-5-[(1R)-1-hydroxytridecyl]-2-furanyl]tridecyl]-2(5H)-f...
Application:	Mitochondrial complex I inhibitor
CAS	111035-65-5
MW:	596.9 D

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