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Item number: TGM-T35317-10mg

Description: Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM). Target: Reductase. Smiles: OC(=O)Cc1nn(Cc2nc3cc(ccc3s2)C(F)(F)F)c(=O)c2ccccc12. References: Mylari BL, et al. Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]...

Keywords:	Zopolrestatum, CP 73850, CP73850, CP-73850
Application:	Targets aldehyde reductase [EC:1.1.1.21] (AKR1B)
CAS	110703-94-1
MW:	419.38 D

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Zopolrestat

Item number: Cay29185-1

Zopolrestat is a potent inhibitor of aldose reductase (IC50s = 1.9 and 41 nM for the human placenta and rat lens enzymes, respectively). It inhibits sorbitol accumulation in human and rat erythrocytes (IC50s = 370 and 220 nM, respectively). Zopolrestat (50 µM) inhibits ethanol-induced aldose reductase activity and...

Keywords:	3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid
Application:	Aldose reductase inhibitor
CAS	110703-94-1
MW:	419.4 D

From 44.00€ *

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