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Item number: AG-CN2-0420-M005

White to off-white solid. Soluble in DMSO or ethanol. Macrolide antibiotic. Ethyl analog of FK506, Strong immunosuppressant. Binds to the FK-506-binding protein FKBP12. This complex inhibits calcineurin (protein phosphatase 2B (PP2B)), Suppresses the production of T helper type 1 (Th1) (interferon and IL-2) and Th2...

Keywords:	Immunomycin, FK520, Analog of FK-506, FR-900520, L-683590, NSC 106410, WS 7238A
Application:	Immunosuppressant, FKBP12 binding, PP2B inhibitor
CAS	11011-38-4
MW:	792 D

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