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Item number: TGM-T1776-100mg

Description: Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4. Target: CXCR, HIV Protease, Virus Protease. Smiles: C(N1CCCNCCNCCC NCC1)c1ccc(CN2CCCNCCNCCCNCC2)cc1. References: Zabel BA, et al. J Immunol. 2009,...

Keywords:	AMD 3100, JM3100, AMD-3329
Application:	Targets C-X-C chemokine receptor type 4 (CXCR4, CD184)
CAS	110078-46-1
MW:	502.78 D

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Plerixafor

Item number: Cay35579-1

Plerixafor is a partial antagonist of chemokine receptor 4 (CXCR4) with IC50 values ranging from 0.02 to 0.13 µg/ml for inhibiting calcium flux in peripheral blood mononuclear cells (PBMCs), various types of T cells, and mouse lymphocytic leukemia cells. It is selective for CXCR4 over CXCR1-3 and CXCR5-9 (IC50s =...

Keywords:	AMD 3100, JM 3100, SDZ SID 791, 1,1'-[1,4-phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane
Application:	CXCR4 partial antagonist, Antineoplastic
CAS	110078-46-1
MW:	502.8 D

From 139.00€ *

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