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SRT 2104
Item number: TGM-T6679-100mg
Description: SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator. Target: Sirtuin. Smiles: Cc1nc(sc1C(=O)Nc1ccccc1-c1cn2c(CN3CCOCC3)csc2n1)-c1cccnc1. References: Mercken EM, et al. Aging Cell. 2014, 13(5), 787-796.
| Keywords: | GSK2245840, sirtuin modulator, SRT2104 |
| Application: | SIRT1 activator |
| CAS | 1093403-33-8 |
| MW: | 516.64 D |
From 40.00€
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SRT 2104
Item number: Cay28380-1
SRT 2104 is an activator of sirtuin 1 (SIRT1). It increases renal SIRT1 activity and protein levels and decreases acetylation of the SIRT1 substrate p53 in a mouse model of diabetes induced by streptozotocin (STZ, Cay-13104), as well as in non-diabetic control animals, when administered at a dose of approximately...
| Keywords: | 4-methyl-N-[2-[3-(4-morpholinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-(3-pyridinyl)-5-thiazolecarboxamide |
| Application: | SIRT1 activator |
| CAS | 1093403-33-8 |
| MW: | 516.6 D |
From 61.00€
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