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Item number: TGM-TQ0101-100mg

Description: MKC3946 is an effective and soluble IRE1alpha inhibitor which triggered modest growth inhibition in multiple myeloma cell lines. Target: IRE1. Smiles: CN1CCN(CC1)C(=O)c1ccc(s1)-c1ccc2c(C=O)c(O)ccc2c1. References: Sun H, et al. Inhibition of IRE1alpha-driven pro-survival pathways is a promising...

Application:	IRE1alpha inhibitor
CAS	1093119-54-0
MW:	380.46 D

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MKC-3946

Item number: Cay19152-1

MKC-3946 is an inhibitor of inositol-requiring enzyme 1alpha (IRE1alpha). It inhibits basal XBP1 splicing, a marker of IRE1alpha activity, in RPMI 8226 multiple myeloma cells in a concentration-dependent manner. MKC-3946 also inhibits XBP1 splicing induced by endoplasmic reticulum (ER) stress and reduces expression...

Keywords:	2-hydroxy-6-[5-[(4-methyl-1-piperazinyl)carbonyl]-2-thienyl]-1-naphthalenecarboxaldehyde
Application:	IRE1alpha inhibitor
CAS	1093119-54-0
MW:	380.5 D

From 76.00€ *

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