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Fumagillol
Item number: TGM-T9155-100mg
Description: Fumagillol is a direct precursor of the potent angiogenesis inhibitors [TNP-470] and (fumagillin). Target: Others, Antibacterial. Smiles: [H][C@@]1([C@H](OC)[C@H](O)CC[C@]11CO1)[C@@]1(C)O[C@@H]1CC=C(C)C. References: Antimicrob Agents Chemother. 2020 Sep 21,64(10):e00582-20. Janak Padia, Liudmila...
| Application: | Bioactive sesquiterpenoid, METAP2 inhibitor |
| CAS | 108102-51-8 |
| MW: | 282.38 D |
From 33.00€
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Fumagillol
Item number: Cay39766-1
Fumagillol is a sesquiterpenoid that has been found in P. jensenii and has diverse biological activities. It is an inhibitor of methionyl aminopeptidase 2 (METAP2, IC50 = 230 nM for the human enzyme). Fumagillol is active against the parasite G. lamblia (IC50 = 3.4 µM). It reduces the proliferation of isolated calf...
| Keywords: | (-)-Fumagillol, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]octan-6-ol |
| Application: | Bioactive sesquiterpenoid, METAP2 inhibitor |
| CAS | 108102-51-8 |
| MW: | 282.4 D |
From 68.00€
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