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CP-466722
Item number: TGM-T6261-100mg
Description: CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK family members in cells. Target: ATM/ATR. Smiles: COc1cc2ncnc(-n3nc(nc3N)-c3ccccn3)c2cc1OC. References: Rainey MD, et al. Cancer Res, 2008, 68(18), 7466-7474.
| Keywords: | CP466722, CP 466722 |
| Application: | ATM inhibitor |
| CAS | 1080622-86-1 |
| MW: | 349.35 D |
From 31.00€
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CP 466,722
Item number: Cay25417-1
CP 466,722 is an inhibitor of ataxia-telangiectasia mutated (ATM) kinase that inhibits ionizing radiation-induced ATM autophosphorylation and phosphorylation of the ATM targets SMC1, Chk2, and p53 in HeLa cells when used at a concentration of 10 µM. It is selective for ATM over PI3K and PIKK in HFF(hTERT) and...
| Keywords: | 1-(6,7-dimethoxy-4-quinazolinyl)-3-(2-pyridinyl)-1H-1,2,4-triazol-5-amine |
| Application: | ATM inhibitor |
| CAS | 1080622-86-1 |
| MW: | 349.4 D |
From 56.00€
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