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Zafirlukast
Item number: TGM-T6736-100mg
Description: Zafirlukast (ICI 204219) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma. Target: Leukotriene Receptor. Smiles: COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C. References: Kassahun K, et al. Chem Res...
| Keywords: | Accolate, ICI 204219, Vanticon |
| Application: | Targets cysteinyl leukotriene receptor 1 (CYSLTR1) |
| CAS | 107753-78-6 |
| MW: | 575.68 D |
From 43.00€
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Zafirlukast
Item number: Cay10008282-10
Zafirlukast is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 0.014 µM in a cell-based calcium mobilization assay). It is selective for CysLT1 over CysLT2 receptors (IC50 = 58 µM). It inhibits mucus secretion induced by leukotriene D4 (LTD4, Cay-20310) in isolated guinea pig trachea (IC50 = 0.6 µM)....
| Keywords: | [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-carbamic acid,... |
| Application: | CysLT1 receptor antagonist |
| CAS | 107753-78-6 |
| MW: | 575.7 D |
From 27.00€
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Zafirlukast
Item number: LKT-Z0222.10
VEGF-C/Nrp2 inhibitor. Leukotriene receptor antagonist.
| Application: | Cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist |
| CAS | 107753-78-6 |
| MW: | 575.68 D |
From 66.00€
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