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NS13001
Item number: TGM-T16345-100mg
Description: NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 µM for SK2 and SK3, respectively. NS13001 holds...
| Keywords: | N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine,... |
| Application: | KCa2.2/SK2 / KCa2.3/SK3 positive allosteric modulator |
| CAS | 1063331-94-1 |
| MW: | 353.81 D |
From 45.00€
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NS 13001
Item number: Cay37317-1
NS 13001 is a positive allosteric modulator for small-conductance calcium-activated potassium channel 2 (KCa2.2/SK2) and KCa2.3/SK3. It increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human KCa2.2/SK2 or KCa2.3/SK3 (EC50s = 1.8 and 0.14 µM, respectively). Oral...
| Keywords: | N-(4-chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine |
| Application: | KCa2.2/SK2 / KCa2.3/SK3 positive allosteric modulator |
| CAS | 1063331-94-1 |
| MW: | 353.8 D |
From 48.00€
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