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Item number: Cay35718-1

S,S-hydroxy Bupropion is an active metabolite of the antidepressant bupropion. It is formed from bupropion by the cytochrome P450 (CYP) isoform CYP2B6. S,S-hydroxy Bupropion inhibits dopamine and norepinephrine but not serotonin (5-HT) reuptake in HEK293 cells expressing the human transporters (IC50s = 0.63, 0.241,...

Keywords:	BUPOH, BW 306U, GW 353162A, Radafaxine, (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol, monohydrochloride
Application:	Bupropion active metabolite, NDRI
CAS	106083-71-0
MW:	292.2 D

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