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15-OxoEDE
15-OxoEDE

Item number: TGM-T84564-10mg

Description: 15-OxoEDE, generated through the oxidation of 15-HEDE, effectively inhibits 5-LO in RBL-1 cells with an IC50 of 55 µM, approximately half as potent as 15(S)-HEDE. Additionally, another related oxo-eicosanoid, 5-oxoETE, is produced from 5(S)-HETE via a specific dehydrogenase, exhibiting significant...
Keywords: 15-KEDE
CAS 105835-44-7
MW: 322.5 D
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15-OxoEDE
15-OxoEDE

Item number: Cay37730-50

15-OxoEDE is produced by the oxidation of 15-HEDE. 15-OxoEDE inhibits 5-LO from RBL-1 cells with an IC50 of 55 µM, which is about 2-fold lower than 15(S)-HEDE. A related oxo-eicosanoid, 5-oxoETE, is biosynthesized from 5(S)-HETE by a specific dehydrogenase and has potent inflammatory activity.Formal Name:...
Keywords: 15-KEDE, 15-oxo-11Z,13E-eicosadienoic acid
Application: 5-LO inhibitor
CAS 105835-44-7
MW: 322.5 D
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