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Anlotinib hydrochloride
Item number: TGM-T85062-10mg
Description: Anlotinib is an orally available inhibitor of multiple tyrosine kinases, including human VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, and c-Kit with IC50 values of 26.9, 0.2, 0.7, 115, and 14.8 nM, respectively. It demonstrates selectivity for these targets over others like c-Met, c-Src, HER2, and EGFR, which...
| Application: | Tyrosine kinase inhibitor |
| CAS | 1058157-76-8 |
| MW: | 443.9 D |
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Anlotinib (hydrochloride)
Item number: Cay27655-1
Anlotinib is an orally bioavailable tyrosine kinase inhibitor that inhibits human VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, and c-Kit (IC50s = 26.9, 0.2, 0.7, 115, and 14.8 nM, respectively). It is selective for these kinases over c-Met, c-Src, HER2, and EGFR (IC50s = >2,000 nM). It also inhibits FGFR1 (IC50 = 11.7 nM for...
| Keywords: | 1-[[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]methyl]-cyclopropanamine, monohydrochloride |
| Application: | Tyrosine kinase inhibitor |
| CAS | 1058157-76-8 |
| MW: | 443.9 D |
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