- Search results for 1051375-16-6
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3 products were found matching "1051375-16-6"!
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Item number: TGM-T6198-100mg
Description: Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. Target: HIV Protease. Smiles: C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12. References:...
Keywords: | S/GSK1349572, GSK1349572 |
Application: | Targets HIV-1 integrase (IN) |
CAS | 1051375-16-6 |
MW: | 419.38 D |
From 31.00€
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Item number: Cay22191-5
Dolutegravir is a potent inhibitor of HIV integrase with an IC50 value of 2.7 nM for HIV-1 integrase-catalyzed strand transfer in vitro. It inhibits HIV-1 viral replication (EC50 = 0.51 nM) in peripheral blood mononuclear cells (PBMCs). The cytotoxic concentration (CC50) values for dolutegravir in unstimulated and...
Keywords: | GSK1349572, S/GSK1349572,... |
Application: | Antiviral, HIV integrase inhibitor |
CAS | 1051375-16-6 |
MW: | 419.4 D |
From 161.00€
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Item number: ESS0193.10mg
C 56.87% H 3.82% F 9.00% N 9.95% O 18.94% D 1.43%
Application: | Labelled analog of Dolutegravir |
CAS | 1051375-16-6 |
MW: | 422.41 D |
From 1,558.00€
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