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RVX-297
RVX-297

Item number: Cay38777-10

RVX-297 is an inhibitor of the bromodomain and extra-terminal domain (BET) family protein bromodomain 2 (BD2). It inhibits BD2 in bromodomain-containing protein 2 (BRD2), BRD3, and BRD4, (IC50s = 0.08, 0.05, and 0.02 µM, respectively) and is selective for BD2 over BD1 (IC50s = 3.76, 2.34, and 1.16 µM for BRD2, BRD3,...
Keywords: 2-[3,5-dimethyl-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-5,7-dimethoxy-4(3H)-quinazolinone
Application: BD2 bromodomain inhibitor
CAS 1044871-04-6
MW: 423.5 D
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