Description: MR2938 is a potent acetylcholinesterase (AChE) inhibitor, evidenced by an IC50 value of 5.04 µM, and significantly inhibits nitric oxide (NO) production with an IC50 of 3.29 µM. Additionally, it mitigates neuroinflammation by blocking the MAPK/JNK and NF-kappaB signaling pathways, making it a promising...

MR2938 is an inhibitor of acetylcholinesterase (AChE, IC50 = 5.04 µM). It is selective for AChE over butyrylcholinesterase (BChE, IC50 = >20 µM). MR2938 inhibits nitric oxide (NO) production in RAW 264.7 cells (IC50 = 3.29 µM). It reverses LPS-induced increases in NF-kappaB and NOD-like receptor protein 3 (NLRP3)...