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Nitisinone
Item number: LKT-N3476.50
Nitisinone is a nitrobenzene inhibitor of HPPD, an enzyme involved in tyrosine degradation. Nitisinone is clinically used to slow the effects of hereditary type 1 tyrosinemia and as a potential treatment for alkaptonuria.
| Keywords: | NTBC, orfadin |
| Application: | 4-hydroxyphenylpyruvate dioxygenase inhibitor |
| CAS | 104206-65-7 |
| MW: | 329.23 D |
From 84.00€
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Nitisinone
Item number: TGM-T1684-100mg
Description: Nitisinone (SC0735)(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor. Target: Others, Reactive Oxygen Species. Smiles: C(=O)(C1=C(N(=O)=O)C=C(C(F)(F)F)C=C1)C2C(=O)CCCC2=O. References: Suwannarat P, et al. Metabolism, 2005. 54(6): p. 719-28.
| Keywords: | SC0735, NTBC, Nitisone |
| Application: | Targets 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] (HPD, hppD) |
| CAS | 104206-65-7 |
| MW: | 329.23 D |
From 40.00€
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Nitisinone
Item number: Cay17924-50
Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway. Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3...
| Keywords: | NTBC, SC-0735, 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione |
| Application: | Reversible 4-hydroxyphenylpyruvate dioxygenase inhibitor |
| CAS | 104206-65-7 |
| MW: | 329.2 D |
From 44.00€
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