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MBX-2982
MBX-2982

Item number: TGM-T1793-100mg

Description: MBX-2982 is a selective, orally available GPR119 agonist used in the treatment of diabetes. Target: GPR. Smiles: CCc1cnc(nc1)N1CCC(CC1)c1ncc(COc2ccc(cc2)-n2cnnn2)s1. References: Hothersall JD, et al. Sustained wash-resistant receptor activation responses of GPR119 agonists. Eur J Pharmacol. 2015 Sep...
Application: GPR119 agonist
CAS 1037792-44-1
MW: 448.54 D
From 46.00€ *
Review
MBX-2982
MBX-2982

Item number: Cay22206-5

MBX-2982 is an agonist of GPR119. It reduces nuclear and total protein levels of sterol regulatory element binding protein 1 (SREBP-1) in HepG2 cells and rat primary hepatocytes under high-glucose and -insulin conditions and increases phosphorylation of the inhibitory form, SREBP-1c. MBX-2982 (10 mg/kg) inhibits...
Keywords: 5-ethyl-2-[4-[4-[[4-(1H-tetrazol-1-yl)phenoxy]methyl]-2-thiazolyl]-1-piperidinyl]-pyrimidine
Application: GPR119 agonist
CAS 1037792-44-1
MW: 448.5 D
From 209.00€ *
Review