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GSK2018682

Item number: TGM-T7360-100mg

Description: GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2,respectively). Target: S1P Receptor, LPL Receptor. Smiles: CC(C)Oc1ncc(cc1Cl)-c1nc(no1)-c1cccc2n(CCCC(O)=O)ccc12. References: Xu J , Gray F , Henderson A , et al. Safety, pharmacokinetics,...

Application:	S1P1 / S1P5 receptor agonist
CAS	1034688-30-6
MW:	440.88 D

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GSK2018682

Item number: Cay31437-5

GSK2018682 is an agonist of sphingosine-1-phosphate receptor 1 (S1P1) and S1P5. It is selective for S1P1 and S1P5 over S1P2, S1P3, and S1P4 receptors. GSK2018682 is efficacious in a mouse model of experimental autoimmune encephalomyelitis (EAE).Formal Name:...

Keywords:	4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-1H-indole-1-butanoic acid
Application:	S1P1 / S1P5 receptor agonist
CAS	1034688-30-6
MW:	440.9 D

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