3 products were found matching "1029712-80-8"!
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Capmatinib
Item number: TGM-T1963-100mg
Description: Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity. Target: Apoptosis, c-Met/HGFR. Smiles: CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1. References: Liu X, et al, Clin Cancer Res, 2011, 17(227). 7127-7138.
| Keywords: | NVP-INC280, INC-280, INCB28060 |
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1029712-80-8 |
| MW: | 412.42 D |
From 43.00€
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INCB 28060
Item number: Cay20056-5
INCB 28060 is an inhibitor of heptatocyte growth factor receptor (HGFR, also known as c-Met), potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM). It blocks cell proliferation and migration or induces apoptosis...
| Keywords: | Capmatinib, INC 280, 2-fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]-benzamide |
| Application: | c-MET inhibitor |
| CAS | 1029712-80-8 |
| MW: | 412.4 D |
From 121.00€
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INCB-28060
Item number: LKT-I5208.1
INCB28060 is an inhibitor of c-Met that exhibits anticancer chemotherapeutic activity. In cellular models of cancer, INCB28060 inhibits cell migration and induces apoptosis, inhibiting proliferation. In animal models, this compound inhibits tumor growth.
| Application: | c-Met inhibitor |
| CAS | 1029712-80-8 |
| MW: | 412.42 D |
From 90.00€
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