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Item number: TGM-T38423-100mg

Description: CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production. Target: Reactive Oxygen Species, TLR. Smiles: CCOCc1nc2c([nH]1)c(N)nc1ccccc21. References: Karama Makni-Maalej, et...

Keywords:	CL097
Application:	TLR7 / TLR8 dual agonist
CAS	1026249-18-2
MW:	242.28 D

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CL097

Item number: Cay39513-1

CL097 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8. It induces activation of NF-kappaB in HEK293 cells expressing human TLR7 or TLR8 when used at concentrations of 0.1 and 1 µg/ml, respectively. CL097 induces TNF-alpha production and enhances LPS- or hyaluronic acid-induced TNF-alpha, IL-10, and IL-12...

Keywords:	2-(ethoxymethyl)-3H-imidazo[4,5-c]quinolin-4-amine
Application:	TLR7 / TLR8 dual agonist
CAS	1026249-18-2
MW:	242.3 D

From 40.00€ *

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