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Lifitegrast
Item number: TGM-T3977-100mg
Description: Lifitegrast (SAR 1118) is an antagonist of lymphocyte function-associated antigen-1. Target: Integrin. Smiles: CS(=O)(=O)c1cccc(C[C@H](NC(=O)c2c(Cl)cc3CN(CCc3c2Cl)C(=O)c2ccc3ccoc3c2)C(O)=O)c1. References: Perez VL, et al. Lifitegrast, a Novel Integrin Antagonist for Treatment of Dry Eye Disease. Ocul...
| Keywords: | SHP-606, SAR 1118 |
| Application: | Targets integrin alpha L (ITGAL, CD11a) |
| CAS | 1025967-78-5 |
| MW: | 615.48 D |
From 34.00€
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Lifitegrast
Item number: Cay22588-10
Lifitegrast is an inhibitor of the protein-protein interaction between lymphocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1). It binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s = 2.98 and 9 nM, respectively) and inhibits the...
| Keywords: | SAR 1118,... |
| Application: | CD11A blocker |
| CAS | 1025967-78-5 |
| MW: | 615.5 D |
From 44.00€
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