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GSK-626616
GSK-626616

Item number: TGM-T15422-100mg

Description: GSK-626616 is a potent and orally bioavailable DYRK3 inhibitor (IC50: 0.7 nM). It inhibits other members of the DYRK family with similar potency. GSK-626616 is a potential therapy for the treatment of anemia. Target: DYRK. Smiles: Clc1cccc(Cl)c1NC1=NC(=O)\C(S1)=C\c1ccc2nccnc2c1. References: Connie L....
Application: DYRK3 inhibitor
CAS 1025821-33-3
MW: 401.27 D
From 44.00€ *
Review
GSK626616
GSK626616

Item number: Cay34621-1

GSK626616 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3, IC50 = 0.7 nM). It enhances erythropoietin-induced erythropoiesis in isolated human bone marrow. GSK626616 increases hemoglobin levels in a mouse model of carboplatin- and radiation-induced anemia.Formal Name:...
Keywords: (5Z)-2-[(2,6-dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone
Application: DYRK3 inhibitor
CAS 1025821-33-3
MW: 401.3 D
From 43.00€ *
Review