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Item number: TGM-T7805-100mg

Description: GW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator. Target: P2X Receptor. Smiles: Cl.Cl.Cc1ccc(CN2CCNCC2)cc1NC(=O)CNc1ccc(F)c(F)c1. References: A D Michel, L J Chambers, D S Walter. Negative and positive allosteric modulators of the P2X7 receptor [J]. British Journal of...

Keywords:	GW791343 (HCl)
Application:	Allosteric purinergic P2X7 receptor modulator
CAS	1019779-04-4
MW:	447.35 D

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GW 791343

Item number: Cay32882-100

GW 791343 is an allosteric modulator of the purinergic P2X7 receptor. It acts as a negative allosteric modulator at human P2X7 receptors but as a positive allosteric modulator at rat P2X7 receptors. GW 791343 (10 and 30 µM) reduces ethidium accumulation induced by the P2X receptor agonists ATP (Cay-14498) or BzATP...

Keywords:	2-[(3,4-difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]-acetamide, dihydrochloride
Application:	Allosteric purinergic P2X7 receptor modulator
CAS	1019779-04-4
MW:	447.4 D

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