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Regorafenib monohydrate
Regorafenib monohydrate

Item number: TGM-T1792L-100mg

Description: Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-beta, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively. Target: VEGFR, c-Kit, c-RET, PDGFR, Autophagy, Raf. Smiles:...
Application: VEGFR2/3 / Ret inhibitor
CAS 1019206-88-2
MW: 500.83 D
From 31.00€ *
Review
Regorafenib
Regorafenib

Item number: LKT-R1626.100

Regorafenib is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor...
Keywords: BAY73-4506, BAY 73-4506, BAY734506, 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide
Application: VEGFR2/3 / Ret inhibitor
CAS 1019206-88-2
MW: 500.83 D
From 60.00€ *
Review