2 products were found matching "1018675-35-8"!
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CVT-12012
Item number: TGM-T6412-100mg
Description: CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD, IC50 = 6.1 nM in HepG2 cells). Target: Stearoyl-CoA Desaturase (SCD). Smiles: Cc1nc2ccc(NCc3cccc(c3)C(F)(F)F)cc2n(CCNC(=O)CO)c1=O. References: Koltun D O , Vasilevich N I , Parkhill E Q , et al. Orally bioavailable,...
| Application: | Stearoyl-coA desaturase (SCD) inhibitor. |
| CAS | 1018675-35-8 |
| MW: | 434.41 D |
From 34.00€
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CVT-12012
Item number: Cay27156-1
CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD, IC50 = 6.1 nM in HepG2 cells). It dose-dependently reduces levels of the SCD desaturation products palmitoleic acid (Cay-10009871) and vaccenic acid in the plasma and liver of rats fed a high-sucrose diet. CVT-12012 (20 mg/kg) also...
| Keywords: | 2-hydroxy-N-[2-[3-methyl-2-oxo-7-[[[3-(trifluoromethyl)phenyl]methyl]amino]-1(2H)-quinoxalinyl]ethyl]-acetamide |
| Application: | Stearoyl-coA desaturase (SCD) inhibitor. |
| CAS | 1018675-35-8 |
| MW: | 434.4 D |
From 43.00€
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