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6(5H)-Phenanthridinone
6(5H)-Phenanthridinone

Item number: TGM-T72017-10mg

Description: 6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-kappaB-induced transcription of the genes encoding TNF-alpha, IL-2, and IFN-gamma in...
Application: PARP1/2 inhibitor
CAS 1015-89-0
MW: 195.22 D
From 86.00€ *
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6(5H)-Phenanthridinone
6(5H)-Phenanthridinone

Item number: Cay28730-10

6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (EC50s = 10.2 and 36.3 µM, respectively, in yeast cells expressing the human enzymes). It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells when used at a concentration of 50 µM....
Keywords: NSC 11021, NSC 40943, NSC 61083
Application: PARP1/2 inhibitor
CAS 1015-89-0
MW: 195.2 D
From 48.00€ *
Review