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Simvastatin (sodium salt)
Item number: Cay10010345-5
Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki = 0.12 nM). Simvastatin reduces plasma cholesterol levels in rats and dogs when administered at doses of 1.2 and 8 mg/kg, respectively. Simvastatin suppresses TNF-induced NF-kappaB activation (IC50 = ~13 µM) and potentiates apoptosis in human myeloid...
| Keywords: | (betaR,deltaR,1S,2S,6R,8S,8aR)-8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-1-nap... |
| Application: | Inhibitor of HMG-CoA reductase |
| CAS | 101314-97-0 |
| MW: | 458.6 D |
From 48.00€
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Simvastatin . sodium salt
Item number: AG-CN2-0539-M005
White to off-white powder. Soluble in water (30mg/ml). Soluble in DMSO, ethanol or DMF (all 10mg/ml). Chemical. CAS: 101314-97-0. Formula: C25H39O6 . Na. MW: 458.6. Synthetic analog of Lovastatin (Prod. No. AG-CN2-0051 http://www.adipogen.com/ag-cn2-0051/lovastatin.html ). Water-soluble carboxylate form of...
| Keywords: | MK-733, Synvinolin, BRN 4768037 |
| CAS | 101314-97-0 |
| MW: | 458,6 D |
From 77.00€
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