- Search results for 1009298-09-2
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4 products were found matching "1009298-09-2"!
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Item number: TGM-T1859-5mg
Description: AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms. Target: Apoptosis, mTOR, Autophagy. Smiles: C[C@@H]1N(C=2C3=C(N=C(N2)N4[C@@H](C)COCC4)N=C(C=C3)C5=CC(CO)=C(OC)C=C5)CCOC1. References: Chresta CM, et al. AZD8055...
Application: | mTOR kinase inhibitor |
CAS | 1009298-09-2 |
MW: | 465.54 D |
From 37.00€
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Item number: Cay16978-1
AZD 8055 is a potent, selective ATP-competitive inhibitor of mTOR, exhibiting an IC50 value of 0.8 nM. It is ~1,000-fold selective for mTOR over all PI3K isoforms and exhibits no activity against a panel of 260 kinases at concentrations up to 10 µM. AZD 8055 inhibits proliferation of A549 and H838 cells with IC50...
Keywords: | CCG-168, 5-[2,4-bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-benzenemethanol |
Application: | mTOR inhibitor |
CAS | 1009298-09-2 |
MW: | 465.5 D |
From 61.00€
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Item number: SYN-1166-M010
Soluble in DMSO or ethanol. AZD8055 is a novel ATP-competitive inhibitor of mTOR kinase activity with an IC(50) of 0.8nM. It shows excellent selectivity (~1,000-fold) against all class I phosphatidylinositol 3-kinase (PI3K) isoforms and other members of the PI3K-like kinase family. Target: mTOR , Kinase Group:...
Keywords: | AZD8055, CCG168 |
Application: | mTOR inhibitor |
CAS | 1009298-09-2 |
MW: | 465,5 D |
From 92.00€
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Item number: LKT-A9914.5
mTOR inhibitor.
Keywords: | AZD-8055 |
Application: | mTOR inhibitor |
CAS | 1009298-09-2 |
MW: | 465.55 D |
From 105.00€
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