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Item number: TGM-T12923-100mg

Description: SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation, effectively inhibiting the TGF-beta1-induced myofibroblast differentiation of fibroblasts. Target: TGF-beta/Smad. Smiles: COc1cc2CCN(Cc2cc1OC)C(=O)\C=C\c1c(-c2ccccc2)n(C)c2ncccc12. References: Jinnin M, et al. Characterization...

Application:	Smad3 phosphorylation inhibitor
CAS	1009104-85-1
MW:	453.53 D

From 732.00€ *

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SMAD3 Inhibitor, SIS3

Item number: Cay15945-1

SMAD3 is a receptor-regulated intracellular protein that functions downstream of TGF-beta and activin receptors and mediates their signaling, playing a role in cell proliferation, differentiation, apoptosis and formation of extracellular matrix. SMAD3 Inhibitor, SIS3 selectively inhibits TGF-beta and activin...

Keywords:	1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one
Application:	Smad3 phosphorylation inhibitor
CAS	1009104-85-1
MW:	453.5 D

From 90.00€ *

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